DPY19L3 Antibody (PACO58212)
- SKU:
- PACO58212
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | DPY19L3 Antibody (PACO58212) |
| Antibody SKU: | PACO58212 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IF:1:200-1:500 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Probable C-mannosyltransferase DPY19L3 protein (587-697AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: SH-SY5Y whole cell lysate, HepG2 whole cell lysate. All lanes: DPY19L3 antibody at 3.4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 84, 63 kDa. Observed band size: 84 kDa. |
 | Immunofluorescence staining of HepG2 cells with PACO58212 at 1:200, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins. |
| Synonyms: | Probable C-mannosyltransferase DPY19L3 (EC 2.4.1) (Dpy-19-like protein 3) (Protein dpy-19 homolog 3), DPY19L3 |
| UniProt Protein Function: | DPY19L3: Belongs to the dpy-19 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 19q13.11Cellular Component: integral to membrane; nuclear inner membraneMolecular Function: mannosyltransferase activityBiological Process: protein amino acid C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q6ZPD9 |
| NCBI GenInfo Identifier: | 289666760 |
| NCBI Gene ID: | 147991 |
| NCBI Accession: | NP_001166245.1 |
| UniProt Secondary Accession: | Q6ZPD9,Q68DC7, Q6ZTB7, Q6ZTS2 |
| UniProt Related Accession: | Q6ZPD9 |
| Molecular Weight: | 83,197 Da |
| NCBI Full Name: | probable C-mannosyltransferase DPY19L3 |
| NCBI Synonym Full Names: | dpy-19-like 3 (C. elegans) |
| NCBI Official Symbol: | DPY19L3Â Â |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | probable C-mannosyltransferase DPY19L3; dpy-19-like protein 3; protein dpy-19 homolog 3 |
| UniProt Protein Name: | Probable C-mannosyltransferase DPY19L3 |
| UniProt Synonym Protein Names: | Dpy-19-like protein 3; Protein dpy-19 homolog 3 |
| Protein Family: | Probable C-mannosyltransferase |
| UniProt Gene Name: | DPY19L3Â Â |
| UniProt Entry Name: | D19L3_HUMAN |