DOCK4 Rabbit Polyclonal Antibody (CAB15764)
- SKU:
- CAB15764
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | DOCK4 Rabbit Polyclonal Antibody |
SKU: | CAB15764 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 150-450 of human DOCK4 (NP_055520.3). |
Sequence: | LDWG NEQL GLDL VPRK EYAM VDPE DISI TELY RLME HRHR KKDT PVQA SSHH LFVQ MKSL MCSN LGEE LEVI FSLF DSKE NRPI SERF FLRL NRNG LPKA PDKP ERHC SLFV DLGS SELR KDIY ITVH IIRI GRMG AGEK KNAC SVQY RRPF GCAV LSIA DLLT GETK DDLI LKVY MCNT ESEW YQIH ENII KKLN ARYN LTGS NAGL AVSL QLLH GDIE QIRR EYSS VFSH GVSI TRKL GFSN IIMP GEMR NDLY ITIE RGEF EKGG KSVA RNVE VTMF IVDS SGQT LKDF ISFG SGEP P |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | DOCK4 |
Positive Sample: | DU145 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Endomembrane system, Peripheral membrane protein, cytosol. |
Calculated MW: | 225kDa |
Observed MW: | 235kDa |
This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated, cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described, but only one has been fully characterized.
Purification Method: | Affinity purification |
Gene ID: | 9732 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |