The DNAJC1 Polyclonal Antibody (PACO08884) is a valuable tool for researchers studying DNAJC1, a member of the DNAJ family of proteins involved in protein folding and chaperone activity. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the DNAJC1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential tool for studies in molecular biology and protein science.DNAJC1, also known as DnaJ homolog subfamily C member 1, is essential for proper protein folding and functioning in the cell. Its role as a molecular chaperone is crucial for maintaining protein homeostasis and preventing protein aggregation, making it a target of interest in research on neurodegenerative diseases, cancer, and other protein folding disorders.
Understanding the function of DNAJC1 is essential for developing therapies that target protein misfolding and aggregation in these diseases.Overall, the DNAJC1 Polyclonal Antibody (PACO08884) is a reliable tool for researchers investigating the role of DNAJC1 in cellular processes and disease mechanisms. Its specificity and sensitivity make it an invaluable asset for studies aiming to unravel the complex functions of DNAJC1 in health and disease.
DnaJ (Hsp40) homolog, subfamily C, member 1;DNAJC1;DNAJL1;ERdj1;HTJ1;MGC131954;MTJ1 ;
UniProt Protein Function:
DNAJC1: May modulate protein synthesis.Protein type: Membrane protein, integral; ChaperoneChromosomal Location of Human Ortholog: 10p12.31Cellular Component: cytosol; endoplasmic reticulum; membraneMolecular Function: ATPase activator activity; protein bindingBiological Process: negative regulation of proteolysis; regulation of protein secretion
UniProt Protein Details:
NCBI Summary:
The membrane protein encoded by this gene is a DNAJ-like heat shock protein that binds the molecular chaperone BiP. In addition, the encoded protein contains two SANT domains that have been shown to bind serpin alpha1-antichymotrypsin and inter-alpha trypsin inhibitor heavy chain 4. [provided by RefSeq, Jul 2016]
