UniProt Protein Function: | Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (). |
UniProt Protein Details: | |
NCBI Summary: | This gene belongs to the dynein family, whose members encode large proteins that are constituents of the microtubule-associated motor protein complex. This complex is composed of dynein heavy, intermediate and light chains, which can be axonemal or cytoplasmic. This protein is an axonemal dynein heavy chain. It is involved in producing force for ciliary beating by using energy from ATP hydrolysis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Dec 2016] |
UniProt Code: | Q8TD57 |
NCBI GenInfo Identifier: | 1119201817 |
NCBI Gene ID: | 55567 |
NCBI Accession: | NP_001334815.1 |
UniProt Secondary Accession: | Q8TD57,O00437, O15437, O43326, Q3C0H2, Q8WUP9, Q9UEM3 Q9UEM5, Q9UG35 |
UniProt Related Accession: | Q8TD57 |
Molecular Weight: | 216,078 Da |
NCBI Full Name: | dynein heavy chain 3, axonemal isoform 2 |
NCBI Synonym Full Names: | dynein axonemal heavy chain 3 |
NCBI Official Symbol: | DNAH3Â Â |
NCBI Official Synonym Symbols: | HDHC8; HEL-36; DNAHC3B; HSADHC3; DNAHC3-BÂ Â |
NCBI Protein Information: | dynein heavy chain 3, axonemal |
UniProt Protein Name: | Dynein heavy chain 3, axonemal |
UniProt Synonym Protein Names: | Axonemal beta dynein heavy chain 3; HsADHC3; Ciliary dynein heavy chain 3; Dnahc3-b |
Protein Family: | Dynein |
UniProt Gene Name: | DNAH3Â Â |
UniProt Entry Name: | |