The Cytokeratin 7 Rabbit Monoclonal Antibody (CAB4765) is a cutting-edge tool for researchers studying cytokeratin 7, a type II cytokeratin expressed in epithelial cells. This high-quality antibody, produced in rabbits, is specifically designed for use in immunohistochemistry (IHC) applications, where it shows strong reactivity with human samples.Cytokeratin 7 is a marker commonly used in cancer research, as its expression pattern can provide valuable information about tumor origin and differentiation. The CAB4765 antibody binds specifically to cytokeratin 7, allowing for precise detection and localization of this protein in a variety of tissue samples. Its reliability and sensitivity make it an essential reagent for studies focusing on epithelial cell biology, tumor biomarker analysis, and diagnostic pathology.
By using the CAB4765 antibody, researchers can gain insights into the role of cytokeratin 7 in normal tissues and disease states, including cancers of the lung, breast, and ovary. The antibody's performance in IHC experiments ensures accurate and reproducible results, facilitating the investigation of cytokeratin 7 functions in development, homeostasis, and pathology. Whether investigating basic biological questions or clinical applications, this monoclonal antibody is a valuable tool for advancing research in the fields of oncology, cell biology, and tissue characterization.
Product Name:
Cytokeratin 7 (KRT7) Rabbit Monoclonal Antibody
SKU:
CAB4765
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Cytokeratin 7 (KRT7) (P08729).
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described.
Purification Method:
Affinity purification
Gene ID:
3855
Clone Number:
ARC1267
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Cytokeratin 7 (KRT7) (KRT7) Rabbit mAb (CAB4765) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
