The CRELD1 Polyclonal Antibody (CAB15186) is specifically designed for research involving CRELD1, a protein known to play a role in embryonic development and is implicated in congenital heart defects. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in various applications, including Western blot and immunohistochemistry.CRELD1, also known as Cysteine-Rich with EGF-Like Domains 1, is crucial for normal heart development and function. Mutations in the CRELD1 gene have been associated with various heart abnormalities, making it a key target for research in cardiology and developmental biology.
The CRELD1 Polyclonal Antibody binds specifically to CRELD1 protein, allowing for accurate detection and study in different cell types and tissues.Researchers in the fields of cardiovascular biology and genetics can benefit from using the CRELD1 Polyclonal Antibody to further understand the mechanisms underlying heart defects and how CRELD1 contributes to embryonic development. By studying CRELD1 expression and function, potential therapeutic targets and interventions for congenital heart diseases may be identified, ultimately leading to improved patient outcomes.
Product Name:
CRELD1 Rabbit Polyclonal Antibody
SKU:
CAB15186
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human CRELD1 (NP_056328.2).
This gene encodes a member of a subfamily of epidermal growth factor-related proteins. The encoded protein is characterized by a cysteine-rich with epidermal growth factor-like domain. This protein may function as a cell adhesion molecule. Mutations in this gene are the cause of atrioventricular septal defect. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
78987
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse lung, using CRELD1 Rabbit pAb (CAB15186) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
