The CPEB2 Polyclonal Antibody (PAC050714) is a valuable tool for researchers studying the CPEB2 protein, a key regulator of mRNA translation and cell cycle progression. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the CPEB2 protein, this antibody enables precise detection and analysis in various cell types, making it ideal for investigations in molecular biology and cancer research.CPEB2, also known as cytoplasmic polyadenylation element-binding protein 2, plays a crucial role in controlling mRNA translation and stability, thereby influencing cellular processes such as cell division, differentiation, and apoptosis.
Its involvement in these fundamental biological functions underscores its relevance in studies on cancer progression, developmental biology, and neurodegenerative diseases. Understanding the mechanisms of CPEB2 can provide insights into potential therapeutic targets for a range of disorders linked to dysregulated gene expression.
Immunofluorescent analysis of Hela cells using PACO50714 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Western Blot. Positive WB detected in: Mouse brain tissue, Rat heart tissue, Rat liver tissue. All lanes: CPEB2 antibody at 2.7µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 65, 63, 62, 107, 110 kDa. Observed band size: 65 kDa.
Background:
May play a role in translational regulation of stored mRNAs in transcriptionally inactive haploid spermatids. Binds to poly(U) RNA oligomers (By similarity).
Synonyms:
Cytoplasmic polyadenylation element-binding protein 2 (CPE-BP2) (CPE-binding protein 2) (hCPEB-2), CPEB2
