ACHA4 Rabbit Polyclonal Antibody (CAB1648)
- SKU:
- CAB1648
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | ACHA4 Rabbit Polyclonal Antibody |
SKU: | CAB1648 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-242 of human ACHA4 (P43681). |
Sequence: | HVET RAHA EERL LKKL FSGY NKWS RPVA NISD VVLV RFGL SIAQ LIDV DEKN QMMT TNVW VKQE WHDY KLRW DPAD YENV TSIR IPSE LIWR PDIV LYNN ADGD FAVT HLTK AHLF HDGR VQWT PPAI YKSS CSID VTFF PFDQ QNCT MKFG SWTY DKAK IDLV NMHS RVDQ LDFW ESGE WVIV DAVG TYNT RKYE CCAE IYPD ITYA FVIR RL |
Tested Applications: | WB ELISA IF |
Recommended Dilution: | WB,1:500 - 1:2000 IF,1:50 - 1:200 |
Synonyms: | EBN; BFNC; EBN1; NACHR; NACRA4; NACHRA4; ACHA4 |
Positive Sample: | Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Lipid-anchor, Multi-pass membrane protein, postsynaptic cell membrane, synapse. |
Calculated MW: | 70kDa |
Observed MW: | 70kDa |
This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 1137 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |