CHAT Rabbit Polyclonal Antibody (CAB2495)
- SKU:
- CAB2495
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Neuroscience
Frequently bought together:
Description
Product Name: | CHAT Rabbit Polyclonal Antibody |
SKU: | CAB2495 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human CHAT (NP_065574.4). |
Sequence: | DMYL NNRL ALPV NSSP AVIF ARQH FPGT DDQL RFAA SLIS GVLS YKAL LDSH SIPT DCAK GQLS GQPL CMKQ YYGL FSSY RLPG HTQD TLVA QNSS IMPE |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | CMS6; CMS1A; CMS1A2; CHOACTASE; CHAT |
Positive Sample: | Raji,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, neuron projection, nucleus, synapse |
Calculated MW: | 83kDa |
Observed MW: | 71kDa |
This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.
Purification Method: | Affinity purification |
Gene ID: | 1103 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |