CDK5RAP2 Rabbit Polyclonal Antibody (CAB15476)
- SKU:
- CAB15476
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CDK5RAP2 Rabbit Polyclonal Antibody |
SKU: | CAB15476 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1744-1893 of human CDK5RAP2 (NP_060719.4). |
Sequence: | GQRL LAEM DIQT QEAP SSTS QELG TKGP HPAP LSKF VSSV STAK LTLE EAYR RLKL LWRV SLPE DGQC PLHC EQIG EMKA EVTK LHKK LFEQ EKKL QNTM KLLQ LSKR QEKV IFDQ LVVT HKIL RKAR GNLE LRPG GAHP GTCS PSRP GS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 |
Synonyms: | C48; MCPH3; Cep215; CDK5RAP2 |
Positive Sample: | LO2,HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Golgi apparatus, centrosome, cytoskeleton, microtubule organizing center. |
Calculated MW: | 215kDa |
Observed MW: | 250kDa |
This gene encodes a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein encoded by this gene is localized to the centrosome and Golgi complex, interacts with CDK5R1 and pericentrin (PCNT), plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 55755 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |