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CD61 monoclonal antibody (FITC) (AGIM0327)

SKU:
AGIM0327
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
CLB-thromb/1, C17
Conjugation:
FITC
Applications:
FC
€179
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Description

system_update_altDatasheet
Product Name:CD61 monoclonal antibody (FITC)
Product Code:AGIM0327
Size:100 µL
Reactivity:Human
Clone:CLB-thromb/1, C17
Applications:Flow Cytometry, Immunofluorescence
Conjugate:FITC
Isotype:IgG1
Host Species:Mouse
Storage:Store at 4°C. Avoid prolonged exposure to light.
Background:CD61 (beta3 integrin) is a transmembrane glycoprotein, which associates with CD41 or CD51 molecules to form heterodimeric adhesion receptores. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. It binds to fibronectin, fibrinogen and von Willebrand factor, and is involved in platelet aggregation. CD51/CD61 complex has similar binding properties and is involved in modulating migration and survival of angiogenic endothelial cells. CD61 is a useful marker of megakaryoblasts and megakaryoblastic leukaemias and inhibits binding of ligand (fibrinogen, fibronectin, etc.). This antibody has been clustered to CD61 in the Fourth, Fifth and Sixth International Workshop on Human White Cell Differentiation Antigens.

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