The CD317 Polyclonal Antibody is a valuable tool for researchers studying the CD317 protein, also known as immune inhibitory receptor, implicated in immune regulation. The antibody, generated in rabbits, demonstrates high reactivity with human samples and has been validated for Western blot applications. By targeting the CD317 protein, this antibody enables detection and analysis in various cell types, making it suitable for investigations in immunology and cancer research.
CD317 plays a crucial role in immune homeostasis by regulating inflammation and inhibiting allergic reactions. Its involvement in immune response modulation makes it a promising target for studying diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the function of CD317 is essential for developing therapies that can manipulate immune function in these diseases.
Product Name:
CD317 Polyclonal Antibody
SKU:
CAB24508
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 55-152 of mouse CD317 (NP_932763.1).
Predicted to enable metalloendopeptidase inhibitor activity and protein homodimerization activity. Involved in several processes, including negative regulation of intracellular transport of viral material; negative regulation of viral genome replication; and response to interferon-gamma. Located in cell surface. Is expressed in retina. Human ortholog(s) of this gene implicated in acquired immunodeficiency syndrome and endometrial cancer. Orthologous to human BST2 (bone marrow stromal cell antigen 2).
Purification Method:
Affinity purification
Gene ID:
69550
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of Mouse ovary, using CD317 Rabbit pAb (CAB24508) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
