The CD1a Monoclonal Antibody (MACO0042) is a valuable tool for researchers studying CD1a, a cell surface glycoprotein involved in immune responses and antigen presentation. This monoclonal antibody, generated using hybridoma technology, shows high specificity and sensitivity in detecting CD1a in human samples. It is suitable for various applications, including immunohistochemistry, flow cytometry, and ELISA.CD1a is a key player in the immune system, presenting lipid antigens to T cells and activating immune responses. Its expression is mainly found on dendritic cells and thymocytes, making it a crucial target for understanding immune function and immune-mediated diseases.
Research on CD1a can provide insights into autoimmune disorders, infectious diseases, and cancer immunotherapy.Overall, the CD1a Monoclonal Antibody (MACO0042) offers researchers a reliable tool for investigating the role of CD1a in immune responses and disease pathology. Its high specificity and versatility make it a valuable addition to studies in immunology, oncology, and infectious diseases.
Product Name:
Anti-CD1A Antibody
Product Sku:
MACO0042
Size:
50ug
Host Species:
Mouse
Tested Applications:
ELISA, IHC
Recommended Dilutions:
IHC:1:100-1:200
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthetic Peptide
Form:
Liquid
Storage Buffer:
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Purification Method:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Clonality:
Monoclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Background:
Synonyms:
T-cell surface glycoprotein CD1a
UniProt Protein Function:
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
NCBI Summary:
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
