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CANX Monoclonal Antibody [PAT18B9AT] (CPAB0680)

SKU:
CPAB0680
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG1
Clone:
PAT18B9AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

CANX Monoclonal Antibody [PAT18B9AT] (CPAB0680)

The CANX Antibody (CPAB0680) is a high-quality polyclonal antibody designed for research involving CANX, a key protein involved in regulating calcium homeostasis and protein folding in the endoplasmic reticulum. The antibody is produced in rabbits and is highly specific for detecting CANX in human samples, making it an essential tool for studies in cellular biology and protein regulation.CANX, also known as calnexin, is a chaperone protein that plays a crucial role in protein folding and quality control within the endoplasmic reticulum. Dysregulation of CANX has been linked to various diseases, including neurodegenerative disorders and cancer.

By targeting CANX with this antibody, researchers can study its function and potential implications in disease pathology.This antibody is validated for use in Western blot applications, allowing for accurate detection and analysis of CANX in various cell types and tissues. Its high reactivity and specificity make it a valuable tool for investigating the role of CANX in cellular processes and disease mechanisms. Researchers in the fields of cell biology, molecular biology, and protein biochemistry will find this antibody essential for their studies on protein folding and quality control mechanisms.

Product Name:CANX Antibody
Product Sku:CPAB0680
Size:5μg
Host Species:Mouse
Immunogen:Anti-human CANX mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CANX protein 21-481 amino acids purified from Ecoli.
Clone:PAT18B9AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:CANX antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG1
Background:Calnexin (CANX) belongs to the calnexin family of molecular chaperones. Calnexin is a calcium-binding, ER-associated protein that interacts briefly with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. Calnexin may also have a key role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Calnexin grants long-term protection of wild-type Shaker protein from ER-associated degradation. Polypeptide substrate recognition by Calnexin requires specific conformations of the Calnexin protein. Calnexin dwindles with aging and might contribute to a cytoprotection in an array of human age-related diseases.
Synonyms:Calnexin, Major histocompatibility complex class I antigen-binding protein p88, p90, IP90, CANX, CNX, FLJ26570.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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