The Cadherin-2 Polyclonal Antibody (CAB3045) is a valuable tool for researchers studying Cadherin-2, a cell adhesion molecule. This antibody, generated in rabbits, demonstrates high specificity and sensitivity for detecting Cadherin-2 in human samples. Validated for use in Western blotting applications, it facilitates the visualization and analysis of Cadherin-2 expression in various cell types.Cadherin-2, also known as N-Cadherin, plays a pivotal role in cell-cell adhesion and signaling processes essential for tissue development and maintenance. Dysregulation of Cadherin-2 expression has been implicated in various diseases, including cancer and neurological disorders.
By targeting Cadherin-2 with this antibody, researchers can gain valuable insights into its function and potential therapeutic applications.The Cadherin-2 Polyclonal Antibody is an invaluable tool for investigations in cell biology, developmental biology, and cancer research. Its ability to specifically detect Cadherin-2 protein levels in experimental samples makes it a versatile reagent for studying the molecular mechanisms underlying cellular adhesion and signaling pathways.
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
100kDa
Observed MW:
80kDa/135kDa/130kDa
This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. This protein plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone.
Purification Method:
Affinity purification
Gene ID:
1000
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse heart using N-Cadherin Rabbit pAb(CAB3045) at 1:1000 dilution.Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L)(CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection:ECL Basic Kit (AbGn00020).Exposuretime:30s.
