The BTN3A2 Monoclonal Antibody (PAC02592) is an essential tool for researchers studying the BTN3A2 protein, which plays a crucial role in immune regulation and activation. This antibody, produced using the hybridoma technology, is highly specific for human samples and is validated for use in various applications, including immunofluorescence and flow cytometry.BTN3A2, a member of the butyrophilin family of proteins, has been linked to the modulation of T cell responses and activation. Its involvement in immune regulation makes it a key target for investigating diseases such as cancer, autoimmune disorders, and infectious diseases.
By enabling researchers to detect and analyze BTN3A2 expression in different cell types, this antibody facilitates in-depth studies into the mechanisms underlying immune dysfunction and potential therapeutic interventions.With its high specificity and sensitivity, the BTN3A2 Monoclonal Antibody (PAC02592) is an indispensable tool for advancing our understanding of immune regulation and developing novel treatments for immune-related diseases.
Antibody Name:
BTN3A2 Antibody (PACO25292)
Antibody SKU:
PACO25292
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human
Immunogen:
Recombinant Human Butyrophilin subfamily 3 member A2 protein (30-248AA)
Plays a role in T-cell responses in the adaptive immune response. Inhibits the release of IFNG from activated T-cells.
Synonyms:
Butyrophilin subfamily 3 member A2, BTN3A2, BT3.2 BTF3 BTF4
UniProt Protein Function:
BTN3A2: a member of the butyrophilin (BTN) family and the immunoglobulin (IG) superfamily. The gene resides in the juxta-telomeric region of the major histocompatability class 1 locus and is clustered with the other six family members, including BTN, BTN2A1, BTN2A2, BTN2A3, BTN3A1, and BTN3A3, on chromosome 6. The full-length protein encoded by this gene is a type I membrane protein. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 6p22.2Cellular Component: membrane; plasma membraneBiological Process: T cell mediated immunity
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the immunoglobulin superfamily, which resides in the juxta-telomeric region of the major histocompatability class 1 locus and is clustered with the other family members on chromosome 6. The encoded protein may be involved in the adaptive immune response. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013]
