BCL6 Rabbit Polyclonal Antibody (CAB7173)
- SKU:
- CAB7173
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | BCL6 Rabbit Polyclonal Antibody |
SKU: | CAB7173 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-280 of human BCL6 (NP_001124317.1). |
Sequence: | MASP ADSC IQFT RHAS DVLL NLNR LRSR DILT DVVI VVSR EQFR AHKT VLMA CSGL FYSI FTDQ LKCN LSVI NLDP EINP EGFC ILLD FMYT SRLN LREG NIMA VMAT AMYL QMEH VVDT CRKF IKAS EAEM VSAI KPPR EEFL NSRM LMPQ DIMA YRGR EVVE NNLP LRSA PGCE SRAF APSL YSGL STPP ASYS MYSH LPVS SLLF SDEE FRDV RMPV ANPF PKER ALPC DSAR PVPG EYSR PTLE VSPN VCHS NIYS PKET IPEE ARSD MHYS VAEG |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:100 |
Synonyms: | BCL5; LAZ3; BCL6A; ZNF51; ZBTB27; BCL6 |
Positive Sample: | Raji |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 79kDa |
Observed MW: | 86kDa |
The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 604 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |