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ASGR1 Rabbit Polyclonal Antibody (CAB16766)

SKU:
CAB16766
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:ASGR1 Rabbit Polyclonal Antibody
SKU:CAB16766
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 62-291 of human ASGR1 (NP_001125.1).
Sequence:EVSK MVKD ALTA IEKP TGDE QSSG CLEN QLPA FLEE LCHE KEIL EKYG HSDC CSQS EEGR HNCF LAHK KPTP ASIP LFQV PEPV TSCE AYEE DRET FMNK FIYE IARR HPFL YAPT ILLW AARY DKII PSCC KAEN AVEC FQTK AATV TKEL RESS LLNQ HACA VMKN FGTR TFQA ITVT KLSQ KFTK VNFT EIQK LVLD VAHV HEHC CRGD VLDC LQDG EKIM SYIC SQ
Tested Applications:IHC-P ELISA
Recommended Dilution:IHC-P,1:50 - 1:200
Synonyms:HL-1; ASGPR; ASGPR1; CLEC4H1; ASGR1
Cellular Localization:Membrane, Secreted, Single-pass type II membrane protein.
Calculated MW:33kDa
Observed MW:Refer to figures

This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Purification Method:Affinity purification
Gene ID:432
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageImmunohistochemistry analysis of paraffin-embedded rat liver using ASGR1 Rabbit pAb (CAB16766) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.

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