ARFGEF1 Rabbit Polyclonal Antibody (CAB16483)
- SKU:
- CAB16483
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
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Description
Product Name: | ARFGEF1 Rabbit Polyclonal Antibody |
SKU: | CAB16483 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 220-420 of human ARFGEF1 (NP_006412.2). |
Sequence: | MEKE RHRQ HHHL LQSP VSHH EPES PQLR YLPP QTVD HISQ EHEG DLDL HTND VDKS LQDD TEPE NGSD ISSA ENEQ TEAD QATA AETL SKNE VLYD GENH DCEE KPQD IVQN IVEE MVNI VVGD MGEG TTIN ASAD GNIG TIED GSDS ENIQ ANGI PGTP ISVA YTPS LPDD RLSV SSND TQES GNSS GPSP GAKF SHIL Q |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | BIG1; P200; DEDISB; ARFGEP1; ARFGEF1 |
Positive Sample: | U-87MG,BxPC-3 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Golgi apparatus, Membrane, Nucleus, Nucleus matrix, nucleolus, perinuclear region, trans-Golgi network. |
Calculated MW: | 209kDa |
Observed MW: | 200kDa |
ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP. It contains a Sec7 domain, which may be responsible for guanine-nucleotide exchange activity and also brefeldin A inhibition.
Purification Method: | Affinity purification |
Gene ID: | 10565 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |