The Anti-SSR2 Antibody (CAB20462) is a polyclonal antibody specifically designed for research involving SSR2, a protein involved in DNA replication and repair processes. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in various applications, including Western blotting.SSR2, a subunit of the single-stranded DNA-binding protein complex, plays a crucial role in maintaining genomic stability and ensuring accurate DNA replication. Dysregulation of SSR2 has been linked to various diseases, including cancer, making it an important target for research in oncology and genetics.
By binding to the SSR2 protein, this antibody enables researchers to detect and analyze SSR2 expression in different cell types, making it an invaluable tool for studies in molecular biology and cancer research. Understanding the function and regulation of SSR2 is essential for advancing our knowledge of DNA replication mechanisms and developing targeted therapies for diseases associated with genomic instability.
Product Name:
SSR2 Rabbit Polyclonal Antibody
SKU:
CAB20462
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 18-145 of human SSR2 (NP_003136.1).
The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2). The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23.
Purification Method:
Affinity purification
Gene ID:
6746
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SSR2 Rabbit pAb (CAB20462) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.