The SOX17 Polyclonal Antibody (CAB18858) is specifically designed for research involving SOX17, a transcription factor known for its role in embryonic development and stem cell differentiation. The antibody, produced in rabbits, is highly specific to human samples and is validated for use in various applications, including Western blot and immunohistochemistry.SOX17 is essential for the development of various tissues and organs, including the gastrointestinal tract, heart, lungs, and pancreas. Its dysregulation has been linked to diseases such as cancer, cardiovascular disorders, and gastrointestinal conditions.
The ability to detect and analyze SOX17 expression in different cell types provides researchers with a valuable tool for studying its function in normal development and disease progression.With its high reactivity and specificity, the SOX17 Polyclonal Antibody is ideal for studies in developmental biology, regenerative medicine, and cancer research. By understanding the molecular mechanisms involving SOX17, researchers can gain insights into potential therapeutic targets for various diseases and conditions.
Product Name:
SOX17 Rabbit Polyclonal Antibody
SKU:
CAB18858
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 343-414 of human SOX17 (NP_071899.1).
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins.
Purification Method:
Affinity purification
Gene ID:
64321
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SOX17 antibody (CAB18858) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 2s.
