The Anti-Pumilio 2 Antibody (CAB19783) is a valuable tool for researchers studying Pumilio 2, a RNA-binding protein known for its role in post-transcriptional regulation of gene expression. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in techniques such as Western blotting.Pumilio 2 is a key player in controlling mRNA translation and stability, making it a crucial protein in processes like cell differentiation, development, and maintenance.
Dysregulation of Pumilio 2 has been linked to various diseases, including cancer and neurological disorders, making it an important target for further investigation.By using this antibody, researchers can easily detect and analyze Pumilio 2 in different cell types, advancing our understanding of its functions and potential therapeutic applications. Its high specificity and reliability make it an essential tool for studies in molecular biology, cell biology, and disease research.
Product Name:
Pumilio 2 Rabbit Monoclonal Antibody
SKU:
CAB19783
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Pumilio 2 (Q8TB72).
Cytoplasm, Cytoplasmic stress granule, Cytosol, Nuclear membrane, Perinuclear region of cytoplasm
Calculated MW:
114kDa
Observed MW:
110-125kDa
This gene encodes a protein that belongs to a family of RNA-binding proteins. The encoded protein functions as a translational repressor during embryonic development and cell differentiation. This protein is also thought to be a positive regulator of cell proliferation in adipose-derived stem cells. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
23369
Clone Number:
ARC2308
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat testis, using Pumilio 2 Rabbit mAb (CAB19783) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
