The Anti-ODC1 Antibody (CAB3898) is a highly specific and sensitive tool for researchers studying ornithine decarboxylase 1 (ODC1), an enzyme involved in polyamine biosynthesis. This polyclonal antibody, produced in rabbits, is validated for use in Western blot applications and is highly reactive with human samples. By binding to ODC1, this antibody enables researchers to detect and analyze the expression of this crucial enzyme in various cell types.ODC1 plays a key role in cell proliferation, making it a target of interest in cancer research and drug development. By studying the expression and activity of ODC1, researchers can gain insights into the regulation of cell growth and potentially identify new therapeutic strategies for cancer treatment.
Additionally, ODC1 has been implicated in other diseases such as inflammation and neurodegenerative disorders, making it a versatile target for a wide range of research applications.Overall, the Anti-ODC1 Antibody (CAB3898) is a valuable tool for investigating the role of ODC1 in various biological processes and diseases. Its high specificity and sensitivity make it a reliable choice for researchers looking to explore the functions of this enzyme in both normal and pathological conditions.
Product Name:
ODC1 Rabbit Monoclonal Antibody
SKU:
CAB3898
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ODC1 (P11926).
This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified.
Purification Method:
Affinity purification
Gene ID:
4953
Clone Number:
ARC0863
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of U-937 cells, using ODC1 antibody (CAB3898) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
