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ODC1 Rabbit Monoclonal Antibody (CAB3898)

SKU:
CAB3898
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
ODC
Research Area:
Metabolism
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:ODC1 Rabbit Monoclonal Antibody
SKU:CAB3898
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ODC1 (P11926).
Sequence:MNNF GNEE FDCH FLDE GFTA KDIL DQKI NEVS SSDD KDAF YVAD LGDI LKKH LRWL KALP RVTP FYAV KCND SKAI VKTL AATG TGFD CASK TEIQ LVQS
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:ODC; BABS; NEDBA; NEDBIA; ODC1
Positive Sample:U-937
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Cytosol
Calculated MW:51kDa
Observed MW:53kDa

This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified.

Purification Method:Affinity purification
Gene ID:4953
Clone Number:ARC0863
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of U-937 cells, using ODC1 antibody (CAB3898) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

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