The MSRB3 Polyclonal Antibody (CAB20980) is a valuable tool for researchers studying MSRB3, a protein involved in mitochondrial dysfunction and oxidative stress response. This antibody, produced in rabbits, shows high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the MSRB3 protein, researchers can detect and analyze its expression in various cell types, making it ideal for studies in biochemistry and cell biology.MSRB3, also known as methionine-R-sulfoxide reductase B3, plays a crucial role in protecting cells from oxidative damage and maintaining redox balance within mitochondria.
Dysregulation of MSRB3 has been implicated in various diseases, including neurodegenerative disorders and metabolic conditions. By understanding the function of MSRB3, researchers can potentially develop targeted therapies to mitigate oxidative stress-related pathologies.Overall, the MSRB3 Polyclonal Antibody is a valuable tool for research into mitochondrial function, oxidative stress response, and their implications for human health. Its high reactivity and specificity make it a reliable reagent for scientists investigating the role of MSRB3 in disease mechanisms and potential therapeutic strategies.
Product Name:
MSRB3 Monoclonal Antibody
SKU:
CAB20980
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 50-192 of human MSRB3 (Q8IXL7).
The protein encoded by this gene catalyzes the reduction of methionine sulfoxide to methionine. This enzyme acts as a monomer and requires zinc as a cofactor. Several transcript variants encoding two different isoforms have been found for this gene. One of the isoforms localizes to mitochondria while the other localizes to endoplasmic reticula.
Purification Method:
Affinity purification
Gene ID:
253827
Clone Number:
ARC2972
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using MSRB3 antibody (CAB20980) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
