The LSD2/KDM1B/AOF1 Polyclonal Antibody (CAB19820) is a valuable tool for researchers investigating LSD2, also known as lysine-specific demethylase 2, KDM1B, or AOF1. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot experiments. By binding to the LSD2/KDM1B/AOF1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an excellent choice for studies in epigenetics and cancer research.
LSD2/KDM1B/AOF1 is a key player in the regulation of gene expression through histone demethylation, influencing processes such as development, differentiation, and disease progression. Understanding the function of LSD2 is crucial for unraveling its role in conditions like cancer and neurological disorders. By targeting LSD2/KDM1B/AOF1, researchers can gain insights into epigenetic mechanisms and potentially identify new therapeutic targets for various diseases.
Product Name:
LSD2/KDM1B/AOF1 Rabbit Monoclonal Antibody
SKU:
CAB19820
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LSD2/KDM1B/AOF1 (NP_694587.3).
Flavin-dependent histone demethylases, such as KDM1B, regulate histone lysine methylation, an epigenetic mark that regulates gene expression and chromatin function (Karytinos et al., 2009 [PubMed 19407342]).
Purification Method:
Affinity purification
Gene ID:
221656
Clone Number:
ARC2347
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using LSD2/AOF1 antibody (CAB19820) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
