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EXOC3 Monoclonal Antibody (CAB20925)

SKU:
CAB20925
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
  • Immunoprecipitation analysis of 300ug extracts of MCF7 cells using 3ug EXOC3 antibody . Western blot was performed from the immunoprecipitate using EXOC3 antibody at a dilition of 1:1000.
  • Western blot analysis of extracts of various cell lines, using EXOC3 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.
$215 - $563
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:EXOC3 Monoclonal Antibody
SKU:CAB20925
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 650-745 of human EXOC3 (O60645).
Sequence:EDVD GYCD TIVA VAEV IKLT DPSL LYLE VSTL VSKY PDIR DDHI GALL AVRG DASR DMKQ TIME TLEQ GPAQ ASPS YVPL FKDI VVPS LNVA KLLK
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:SEC6; Sec6p; SEC6L1; EXOC3
Positive Sample:HeLa,HepG2,MCF7,U-251MG,Mouse brain,Rat brain
Conjugate:Unconjugated
Cellular Localization:cytosol, exocyst, Golgi apparatus, growth cone, perinuclear region of cytoplasm, presynaptic membrane
Calculated MW:86kDa
Observed MW:85kDa

The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.

Purification Method:Affinity purification
Gene ID:11336
Clone Number:ARC2900
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using EXOC3 antibody (CAB20925) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.

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