Factor H Rabbit Monoclonal Antibody (CAB8798)
- SKU:
- CAB8798
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- AHUS1
- AMBP1
- ARMD4
- ARMS1
- CFHL3
- FH
- FHL1
- HF
- HF1
- HF2
- HUS
Frequently bought together:
Description
Product Name: | Factor H Rabbit Monoclonal Antibody |
SKU: | CAB8798 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Complement factor H (P08603). |
Sequence: | GGNV FEYG VKAV YTCN EGYQ LLGE INYR ECDT DGWT NDIP ICEV VKCL PVTA PENG KIVS SAME PDRE YHFG QAVR FVCN SGYK IEGD EEMH CSDD GFWS K |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | FH; HF; HF1; HF2; HUS; FHL1; AHUS1; AMBP1; ARMD4; ARMS1; CFHL3; Complement factor H |
Positive Sample: | BxPC-3 |
Conjugate: | Unconjugated |
Cellular Localization: | blood microparticle, extracellular exosome, extracellular region, extracellular space |
Calculated MW: | 139kDa |
Observed MW: | 160kDa |
This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Purification Method: | Affinity purification |
Gene ID: | 3075 |
Clone Number: | ARC1306 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |