The Anti-CD74 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0325) is a cutting-edge tool for researchers studying the CD74 protein, a key player in immune response regulation. This antibody, specially developed using advanced chimeric recombinant technology, provides high specificity and sensitivity for detecting CD74 in human samples.With its unique design, the antibody enables precise detection and analysis of CD74 in various cell types, making it an invaluable resource for studies in immunology and cancer research. The CD74 protein, also known as the MHC class II-associated invariant chain, is involved in antigen presentation and immune response modulation, making it a critical target for investigation in diseases like cancer, autoimmune disorders, and inflammatory conditions.
By utilizing the Anti-CD74 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0325), researchers can gain valuable insights into the role of CD74 in immune regulation and disease pathology. This innovative antibody offers a reliable and efficient solution for exploring the functions of CD74 and developing potential therapeutic strategies targeting this important protein.
SKU:
HDAB0325
Size:
100 µg
Clonality:
Monoclonal
Clone:
DMC674
Synonyms:
DHLAG; HLADG; Ia-GAMMA; II; p33
Applications:
Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]