The ADSS Polyclonal Antibody (CAB12398) is a valuable tool for researchers studying the ADSS protein, a key enzyme involved in the purine biosynthetic pathway. This antibody, generated in rabbits, boasts high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the ADSS protein, researchers can accurately detect and analyze this important molecule in various cell types.ADSS, also known as adenylosuccinate synthase, plays a crucial role in the production of purine nucleotides, which are essential for various cellular processes including DNA and RNA synthesis. Dysregulation of purine biosynthesis has been linked to various human diseases, making ADSS an attractive target for therapeutic interventions.
By studying the function and regulation of ADSS, researchers can gain insights into diseases such as cancer, neurological disorders, and metabolic conditions.The ADSS Polyclonal Antibody offers researchers a reliable tool for investigating the role of ADSS in health and disease. Its high specificity and sensitivity make it ideal for studies in biochemistry, molecular biology, and drug discovery. By elucidating the mechanisms of ADSS function, researchers can pave the way for the development of novel therapeutic strategies targeting purine metabolism.
Product Name:
ADSS Rabbit Polyclonal Antibody
SKU:
CAB12398
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ADSS (NP_001117.2).
This gene encodes the enzyme adenylosuccinate synthetase which catalyzes the first committed step in the conversion of inosine monophosphate to adenosine monophosphate. A pseudogene of this gene is found on chromosome 17.
Purification Method:
Affinity purification
Gene ID:
159
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using ADSS Rabbit pAb (CAB12398) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
