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ACY1 Monoclonal Antibody [PAT1E2AT] (CPAB0194)

SKU:
CPAB0194
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT1E2AT
Applications:
WB
ELISA
€149
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Description

system_update_alt Datasheet

ACY1 Monoclonal Antibody [PAT1E2AT] (CPAB0194)

The ACY1 Polyclonal Antibody (CPAB0194) is a valuable tool for researchers studying ACY1, an enzyme involved in metabolic processes and amino acid degradation. This antibody, produced in rabbits, exhibits high specificity for human samples and has been validated for use in Western blot applications. By binding to the ACY1 protein, this antibody enables the detection and analysis of ACY1 levels in various cell types, making it an essential component for studies in biochemistry and molecular biology.

ACY1 plays a crucial role in maintaining cellular homeostasis by regulating the breakdown of amino acids and promoting metabolic stability. Dysregulation of ACY1 activity has been linked to various metabolic disorders and diseases, making it a key target for research in fields such as metabolism, genetics, and drug development. Understanding the function of ACY1 is essential for uncovering its role in health and disease, and for developing targeted therapies to treat ACY1-related conditions.

Product Name:ACY1 Antibody
Product Sku:CPAB0194
Size:5μg
Host Species:Mouse
Immunogen:Anti-human ACY1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human ACY1 amino acids 1-48 purified from Ecoli.
Clone:PAT1E2AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:ACY1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2b
Background:ACY1 is a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and acyl group, and has been postulated to take part in the catabolism and salvage of acylated amino acids. Defects in ACY1 are the source of aminoacylase-1 deficiency (ACY1D). ACY1D results in a metabolic disorder manifesting with encephalopathy, unspecific psychomotor delay, psychomotor delay with atrophy of the vermis and syringomyelia, marked muscular hypotonia or normal clinical features. Epileptic seizures are a frequent feature.
Synonyms:ACY1D, ACYLASE, ACY-1, EC 3.5.1.143.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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