The ABCA9 Antibody (PAC037730) is a valuable tool for researchers studying the ATP-binding cassette sub-family A member 9 (ABCA9) protein. This polyolonal antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. It binds specifically to the ABCA9 protein, allowing for detection and analysis in a variety of cell types.ABCA9 is a member of the ABC transporter family, known for its role in lipid transport and cellular homeostasis. Research has shown that ABCA9 may be involved in cholesterol metabolism and atherogenesis, making it a potential target for cardiovascular disease studies.
Additionally, ABCA9 has been implicated in the regulation of immune response and inflammation, suggesting its involvement in the pathogenesis of inflammatory diseases.By using the ABCA9 Antibody, researchers can gain insight into the function and regulation of ABCA9 in various cellular processes. This antibody is a valuable tool for studies in lipid metabolism, cardiovascular disease, inflammation, and immune modulation. Its high specificity and reliability make it an ideal choice for researchers investigating the role of ABCA9 in health and disease.
Antibody Name:
ABCA9 Antibody (PACO37730)
Antibody SKU:
PACO37730
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
ELISA:1:2000-1:10000, IF:1:50-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human ATP-binding cassette sub-family A member 9 protein (106-220AA)
Immunofluorescent analysis of Hela cells using PACO37730 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
May play a role in monocyte differentiation and lipid homeostasis.
Synonyms:
ATP-binding cassette sub-family A member 9, ABCA9
UniProt Protein Function:
ABCA9: May play a role in monocyte differentiation and lipid homeostasis. Belongs to the ABC transporter superfamily. ABCA family. 5 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Transporter, ABC family; Transporter; Membrane protein, multi-passChromosomal Location of Human Ortholog: 17q24.2Cellular Component: mitochondrion; integral to membraneMolecular Function: transporter activity; ATPase activity; ATP bindingBiological Process: metabolic process; transport
UniProt Protein Details:
NCBI Summary:
This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two transmembrane domains and two nucleotide binding folds. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This gene is a member of the ABC1 subfamily and is clustered with four other ABC1 family members on chromosome 17q24. Transcriptional expression of this gene is induced during monocyte differentiation into macrophages and is suppressed by cholesterol import. [provided by RefSeq, Jul 2008]
