ZWINT Rabbit Polyclonal Antibody (CAB6328)
- SKU:
- CAB6328
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | ZWINT Rabbit Polyclonal Antibody |
SKU: | CAB6328 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-277 of human ZWINT (NP_008988.2). |
Sequence: | MEAA ETEA EAAA LEVL AEVA GILE PVGL QEEA ELPA KILV EFVV DSQK KDKL LCSQ LQVA DFLQ NILA QEDT AKGL DPLA SEDT SRQK AIAA KEQW KELK ATYR EHVE AIKI GLTK ALTQ MEEA QRKR TQLR EAFE QLQA KKQM AMEK RRAV QNQW QLQQ EKHL QHLA EVSA EVRE RKTG TQQE LDRV FQKL GNLK QQAE QERD KLQR YQTF LQLL YTLQ GKLL FPEA EAEA ENLP DDKP QQPT RPQE QSTG DTMG RDPG VSFK AVGL QPAG DVNL P |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | SIP30; ZWINT1; KNTC2AP; HZwint-1; ZWINT |
Positive Sample: | 293T,SW620,HepG2,Jurkat,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Nucleus, centromere, kinetochore. |
Calculated MW: | 31kDa |
Observed MW: | 39kDa |
This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 11130 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |