The ZSCAN4 Polyclonal Antibody (CAB12015) is a valuable tool for researchers studying the ZSCAN4 protein, a critical player in stem cell biology and embryo development. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.ZSCAN4, a key transcription factor, is involved in regulating telomere maintenance, cell cycle progression, and pluripotency of embryonic stem cells. Its function in maintaining genomic stability and regulating cellular differentiation makes it a target of interest in fields like regenerative medicine and cancer research.
By binding to the ZSCAN4 protein, this polyclonal antibody enables researchers to detect and analyze its expression in various cell types, providing valuable insights into its role in cellular processes. Understanding the mechanisms of ZSCAN4 activity is essential for advancing our knowledge of stem cell biology and potentially unlocking new therapeutic interventions in areas like regenerative medicine and cancer treatment.
Product Name:
ZSCAN4 Rabbit Polyclonal Antibody
SKU:
CAB12015
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-227 of human ZSCAN4 (NP_689890.1).
The ZSCAN4 gene encodes a protein involved in telomere maintenance and with a key role in the critical feature of mouse embryonic stem (ES) cells, namely, defying cellular senescence and maintaining normal karyotype for many cell divisions in culture (Zalzman et al., 2010 [PubMed 20336070]).
Purification Method:
Affinity purification
Gene ID:
201516
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and 293T cells transfected with ZSCAN4, using ZSCAN4 Rabbit pAb (CAB12015) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
