The ZSCAN25 Monoclonal Antibody (PACO22706) is a specialized tool for researchers studying ZSCAN25, a protein involved in various cellular processes including DNA replication and regulation of pluripotency. This antibody, generated from mouse hybridoma cells, is highly specific for human samples and is validated for use in immunofluorescence and flow cytometry applications. ZSCAN25 is a key player in maintaining genomic stability and controlling stem cell function, making it a target of interest in stem cell research and cancer biology. By binding to the ZSCAN25 protein, this antibody allows for the visualization and analysis of ZSCAN25 expression in different cell populations, providing valuable insights into its function and potential therapeutic implications.
The versatility of the ZSCAN25 Monoclonal Antibody makes it a valuable tool for researchers investigating mechanisms of DNA repair, cell cycle regulation, and stem cell maintenance. Its high specificity and sensitivity make it a reliable choice for various experimental techniques, aiding in the advancement of scientific understanding in the fields of developmental biology and regenerative medicine.
Antibody Name:
ZSCAN25 Antibody (PACO22706)
Antibody SKU:
PACO22706
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human ZNF498.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from COS-7 cells, using ZNF498 antibody.
Background:
May be involved in transcriptional regulation By similarity.
Synonyms:
Zinc finger protein 498; Zinc finger and SCAN domain-containing protein 25; ZNF498; ZSCAN25;
UniProt Protein Function:
ZNF498: May be involved in transcriptional regulation. Belongs to the krueppel C2H2-type zinc-finger protein family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: DNA-binding; C2H2-type zinc finger protein; Transcription factorChromosomal Location of Human Ortholog: 7q22.1Cellular Component: nucleusMolecular Function: sequence-specific DNA binding; transcription factor activity
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein that bears some similarity to zinc finger proteins, which are involved in DNA binding and protein-protein interactions. Multiple alternatively spliced transcript variants have been identified, but the full-length nature for most of them has not been determined. [provided by RefSeq, Jul 2008]
