The ZSCAN25 Polyclonal Antibody (PACO01730) is a research tool designed for investigating the ZSCAN25 protein, a key player in cellular processes such as telomere maintenance and genome stability. This antibody, generated in rabbits, exhibits high specificity towards human samples and is validated for use in Western blotting applications. By binding to the ZSCAN25 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential tool for studies in molecular biology and cancer research.ZSCAN25 is a critical factor in the regulation of telomere length and genomic stability, making it a promising target for research on aging, cancer, and genetic diseases.
Understanding the function and regulation of ZSCAN25 is essential for unraveling its role in these complex biological processes and developing targeted therapies for diseases associated with telomere dysfunction and genomic instability. This antibody provides researchers with a valuable tool for exploring the intricate mechanisms underlying these important cellular pathways.
Antibody Name:
ZSCAN25 Antibody
Antibody SKU:
PACO01730
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human, Monkey
Immunogen:
synthesized peptide derived from the C-terminal region of human ZNF498.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
ZNF498; ZSCAN25; Zinc finger protein 498; Zinc finger and SCAN domain-containing protein 25
UniProt Protein Function:
ZNF498: May be involved in transcriptional regulation. Belongs to the krueppel C2H2-type zinc-finger protein family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: DNA-binding; C2H2-type zinc finger protein; Transcription factorChromosomal Location of Human Ortholog: 7q22.1Cellular Component: nucleusMolecular Function: sequence-specific DNA binding; transcription factor activity
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein that bears some similarity to zinc finger proteins, which are involved in DNA binding and protein-protein interactions. Multiple alternatively spliced transcript variants have been identified, but the full-length nature for most of them has not been determined. [provided by RefSeq, Jul 2008]
