The ZSCAN22 Polyclonal Antibody (PAC023499) is a research tool designed for studying the ZSCAN22 protein, a key factor involved in genomic stability and telomere maintenance. This antibody, produced in rabbits, exhibits high specificity and reactivity with human samples, making it a reliable tool for Western blot applications. By binding to the ZSCAN22 protein, researchers can accurately detect and analyze its expression in various cell types, providing valuable insights for studies in genetics and cancer research.ZSCAN22 is a crucial player in maintaining genomic integrity by regulating telomere length and stability, which are essential for preventing chromosomal abnormalities and cell aging.
Its role in DNA replication and repair processes highlights its importance in cancer development and progression. Research into ZSCAN22 can offer new perspectives on how genomic instability contributes to tumorigenesis and may lead to the development of novel therapies targeting this pathway.Overall, the ZSCAN22 Polyclonal Antibody is a valuable tool for researchers interested in understanding the molecular mechanisms governing genomic stability and its impact on cancer biology. Its high specificity and reliability make it an ideal choice for exploring the functions of ZSCAN22 in various cellular processes, leading to potential advancements in cancer treatment and personalized medicine.
Synthesized peptide derived from internal of human ZSCAN22.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from K562 cells, using ZSCAN22 antibody.
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using ZSCAN22 antibody.
Background:
May be involved in transcriptional regulation.
Synonyms:
Zinc finger and SCAN domain-containing protein 22; Zinc finger protein 50; Krueppel-related zinc finger protein 2; Protein HKR2; ZSCAN22
UniProt Protein Function:
HKR2: May be involved in transcriptional regulation. Belongs to the krueppel C2H2-type zinc-finger protein family.Protein type: C2H2-type zinc finger protein; Transcription factor; DNA-bindingChromosomal Location of Human Ortholog: 19q13.43Cellular Component: nucleusMolecular Function: protein binding; sequence-specific DNA binding; transcription factor activity
