The ZSCAN16 Polyclonal Antibody (PAC021953) is a valuable tool for researchers studying ZSCAN16, a zinc finger protein involved in telomere maintenance and genome stability. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications, including Western blot and immunofluorescence.ZSCAN16 plays a crucial role in the regulation of telomere lengthening and genome integrity, making it a key player in cell division and aging processes. By targeting ZSCAN16 with this antibody, researchers can effectively detect and study the protein in different cell types and tissues, providing insights into its functions in DNA replication and repair.
With its application in telomere biology and genome stability research, the ZSCAN16 Polyclonal Antibody offers great potential for investigating diseases related to abnormal cell proliferation and DNA damage, such as cancer and aging-related disorders. By unraveling the mechanisms of ZSCAN16, researchers can pave the way for novel therapeutic strategies targeting telomere maintenance and genomic stability.
Antibody Name:
ZSCAN16 Antibody (PACO21953)
Antibody SKU:
PACO21953
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human ZNF435.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from NIH-3T3 cells and HT-29 cells, using ZNF435 antibody.
Background:
May be involved in transcriptional regulation. Mungall A.J., Nature 425:805-811(2003).
Synonyms:
Zinc finger and SCAN domain-containing protein 16; Zinc finger protein 435; Zinc finger protein 392; ZSCAN16; ZNF392
