The ZSCAN1 Polyclonal Antibody (CAB16639) is a valuable tool for researchers studying ZSCAN1, a zinc finger protein involved in the regulation of telomere maintenance and genomic stability. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the ZSCAN1 protein, researchers can accurately detect and analyze its expression in various cell types, making it an essential reagent for investigations in genetics and cancer research.ZSCAN1 is known for its role in maintaining genomic integrity by regulating telomere length and stability, crucial for preventing chromosomal abnormalities and cell senescence.
Its involvement in DNA replication and repair processes suggests its potential significance in cancer development and progression. By studying ZSCAN1 activity, researchers can uncover new insights into cellular mechanisms that drive tumorigenesis and potentially identify novel therapeutic targets for cancer treatment.Overall, the ZSCAN1 Polyclonal Antibody is a valuable tool for researchers seeking to explore the functions and implications of ZSCAN1 in telomere biology, genomic stability, and cancer development. Its specificity and sensitivity make it an ideal choice for studies aiming to elucidate the molecular mechanisms underlying these processes.
Product Name:
ZSCAN1 Rabbit Polyclonal Antibody
SKU:
CAB16639
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 300-400 of human ZSCAN1 (NP_872378.3).
Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of chromatin.
Purification Method:
Affinity purification
Gene ID:
284312
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and 293T cells transfected with ZSCAN1 using ZSCAN1 Rabbit pAb (CAB16639) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
