null

ZRANB2 Antibody (PACO31528)

SKU:
PACO31528
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€339

Description

system_update_altDatasheetsystem_update_altMSDS

ZRANB2 Antibody (PACO31528)

The Zranb2 Polyclonal Antibody (PACO31528) is specifically designed for researchers studying Zranb2, a protein involved in RNA processing and gene regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including Western blot. By binding to the Zranb2 protein, this antibody enables precise detection and analysis in different cell types, making it an excellent tool for studies in molecular biology and gene expression.Zranb2, also known as Zinc finger RAN-binding domain containing 2, plays a crucial role in RNA metabolism, participating in processes such as splicing and transcriptional regulation.

Its importance in gene expression regulation makes it a valuable target for research exploring various biological pathways and disease mechanisms. Studying the function of Zranb2 can provide insights into conditions like cancer, neurodegenerative diseases, and genetic disorders, potentially leading to the development of novel therapeutic strategies targeting RNA processing pathways.

Antibody Name:ZRANB2 Antibody (PACO31528)
Antibody SKU:PACO31528
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, IHC
Recommended Dilutions:ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:Human
Immunogen:Recombinant Human Zinc finger Ran-binding domain-containing protein 2 protein (1-320AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:>95%, Protein G purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Product ImageImmunohistochemistry of paraffin-embedded human placenta tissue using PACO31528 at dilution of 1:100.
Background:Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'-splice site selection.
Synonyms:Zinc finger Ran-binding domain-containing protein 2 (Zinc finger protein 265) (Zinc finger, splicing), ZRANB2, ZIS ZNF265
UniProt Protein Function:ZNF265: Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'- splice site selection. Belongs to the ZRANB2 family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:RNA-binding

Chromosomal Location of Human Ortholog: 1p31

Cellular Component: nucleoplasm; nucleus

Molecular Function:protein binding; RNA binding; transcription factor activity; zinc ion binding

Biological Process: mRNA processing; regulation of transcription, DNA-dependent; RNA splicing

UniProt Code:O95218
NCBI GenInfo Identifier:146291106
NCBI Gene ID:9406
NCBI Accession:O95218.2
UniProt Secondary Accession:O95218,Q53GS3, Q59F92, Q5VV33, Q5VV34, Q8IXN6, Q9UP63 D3DQ75,
UniProt Related Accession:O95218
Molecular Weight:36,318 Da
NCBI Full Name:Zinc finger Ran-binding domain-containing protein 2
NCBI Synonym Full Names:zinc finger RANBP2-type containing 2
NCBI Official Symbol:ZRANB2  
NCBI Official Synonym Symbols:ZIS; ZIS1; ZIS2; ZNF265  
NCBI Protein Information:zinc finger Ran-binding domain-containing protein 2
UniProt Protein Name:Zinc finger Ran-binding domain-containing protein 2
UniProt Synonym Protein Names:Zinc finger protein 265; Zinc finger, splicing
Protein Family:Zinc finger Ran-binding domain-containing protein
UniProt Gene Name:ZRANB2  
UniProt Entry Name:ZRAB2_HUMAN
AntibodiesELISA Kits
ZRANB2 Antibody (PACO01723)ZNF265 Colorimetric Cell-Based ELISA
Secondary Antibody
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)
Recommended Products
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011)
Anti-HRP-conjugated Beta Actin Antibody (CABC028)

Related Products