The ZRANB2 Polyclonal Antibody (PAC023180) is specifically designed for researchers studying the ZRANB2 protein, a key player in DNA repair and maintenance. This antibody is raised in rabbits and has been shown to be highly reactive with human samples, making it ideal for use in Western blot applications. By targeting the ZRANB2 protein, this antibody enables accurate detection and analysis in a variety of cell types, providing valuable insights for studies in genetics, cancer research, and beyond.The ZRANB2 protein, also known as Zinc finger RANBP2-type containing 2, is essential for maintaining genomic stability by regulating DNA replication and repair processes.
Dysregulation of ZRANB2 has been linked to various diseases, including cancer and neurodegenerative disorders, highlighting its importance in cellular health. By understanding the function and regulation of ZRANB2, researchers can uncover potential therapeutic targets for treating these conditions and advancing precision medicine approaches.
Synthesized peptide derived from internal of human ZNF265.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from HeLa cells, using ZNF265 antibody.
Immunofluorescence analysis of HUVEC cells, using ZNF265 antibody.
Background:
Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'-splice site selection.
Synonyms:
Z265; ZIS; ZN265; Zinc finger protein 265; Zinc finger
UniProt Protein Function:
ZNF265: Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'- splice site selection. Belongs to the ZRANB2 family. 2 isoforms of the human protein are produced by alternative splicing.
