ZPR1 Rabbit Polyclonal Antibody (CAB15746)
- SKU:
- CAB15746
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
Product Name: | ZPR1 Rabbit Polyclonal Antibody |
SKU: | CAB15746 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 110-459 of human ZPR1 (NP_003895.1). |
Sequence: | LEDM NREV VKTD SAAT RIPE LDFE IPAF SQKG ALTT VEGL ITRA ISGL EQDQ PARR ANKD ATAE RIDE FIVK LKEL KQVA SPFT LIID DPSG NSFV ENPH APQK DDAL VITH YNRT RQQE EMLG LQEE APAE KPEE EDLR NEVL QFST NCPE CNAP AQTN MKLV QIPH FKEV IIMA TNCE NCGH RTNE VKSG GAVE PLGT RITL HITD ASDM TRDL LKSE TCSV EIPE LEFE LGMA VLGG KFTT LEGL LKDI RELV TKNP FTLG DSSN PGQT ERLQ EFSQ KMDQ IIEG NMKA HFIM DDPA GNSY LQNV YAPE DDPE MKVE RYKR TFDQ NEEL GLND MKTE GYEA GLAP QR |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | GKAF; ZNF259; ZPR1 |
Positive Sample: | U-87MG |
Conjugate: | Unconjugated |
Cellular Localization: | Cajal body, Cell projection, Cytoplasm, Nucleus, axon, gem, growth cone, nucleolus, perinuclear region. |
Calculated MW: | 51kDa |
Observed MW: | 55kDa |
The protein encoded by this gene is found in the cytoplasm of quiescent cells but translocates to the nucleolus in proliferating cells. The encoded protein interacts with survival motor neuron protein (SMN1) to enhance pre-mRNA splicing and to induce neuronal differentiation and axonal growth. Defects in this gene or the SMN1 gene can cause spinal muscular atrophy. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 8882 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |