The ZP1 Polyclonal Antibody (CAB10776) is a valuable tool for researchers studying the ZP1 protein, which is involved in various cellular processes such as cell signaling and gene expression regulation. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the ZP1 protein, this antibody allows for the detection and analysis of ZP1 in a variety of cell types, making it an excellent choice for studies in molecular biology and cell signaling research.ZP1, also known as zona pellucida protein 1, is essential for proper fertilization and embryo development. Its role in mediating sperm-egg interactions makes it a key target for research in reproductive biology and fertility treatments.
Understanding the function and regulation of ZP1 can provide insights into infertility issues and reproductive disorders, leading to the development of more effective therapeutic interventions.Overall, the ZP1 Polyclonal Antibody (CAB10776) offers researchers a reliable tool for studying the biological functions of the ZP1 protein in various physiological and pathological contexts. Its specificity and sensitivity make it a valuable asset for advancing our understanding of cellular processes and developing targeted therapies for reproductive health disorders.
Product Name:
ZP1 Rabbit Polyclonal Antibody
SKU:
CAB10776
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 340-610 of human ZP1 (NP_997224.2).
Cell membrane, Secreted, Single-pass type I membrane protein, extracellular matrix, extracellular space.
Calculated MW:
70kDa
Observed MW:
70kDa
The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene ensures the structural integrity of the zona pellucida. Mutations in this gene are a cause of oocyte maturation defect and infertility.
Purification Method:
Affinity purification
Gene ID:
22917
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ZP1 Rabbit pAb (CAB10776) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
