The ZOT Antibody (PAC061822) is a polyclonal antibody specifically designed for research involving Zonula Occludens Toxin (ZOT), a protein that plays a crucial role in the regulation of tight junctions in intestinal epithelial cells. This antibody, produced in rabbits, is highly reactive with ZOT protein in various samples and has been validated for use in Western blot applications.ZOT is known for its ability to disrupt the integrity of intestinal barrier function, leading to increased permeability and potential inflammation in the gut. Research on ZOT is important for understanding the mechanisms of intestinal barrier dysfunction in conditions such as inflammatory bowel disease and leaky gut syndrome.
By targeting ZOT, researchers can investigate potential therapeutic strategies to restore gut barrier function and alleviate associated inflammatory conditions.Overall, the ZOT Antibody is a valuable tool for studying the role of Zonula Occludens Toxin in intestinal barrier function and inflammatory processes, making it an essential resource for researchers in the fields of gastroenterology, immunology, and microbiology.
Antibody Name:
zot Antibody (PACO61822)
Antibody SKU:
PACO61822
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:5000
Species Reactivity:
Vibrio cholerae serotype O1
Immunogen:
Recombinant Vibrio cholerae serotype O1 Zona occludens toxin protein (1-399AA)
Western Blot. Positive WB detected in Recombinant protein. All lanes: zot antibody at 3.5µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 52 kDa. Observed band size: 52 kDa.
Background:
Increases the permeability of the small intestine mucosa by affecting the structure of intercellular tight junctions (zonula occludens).
Synonyms:
Zona occludens toxin (Zonular occludens toxin) (Zot), zot
UniProt Protein Function:
Increases the permeability of the small intestine mucosa by affecting the structure of intercellular tight junctions (zonula occludens).
