The ZNRF2 Polyclonal Antibody (PAC013669) is a valuable tool for researchers studying ZNRF2, a protein involved in the regulation of cellular processes and signaling pathways. This antibody, produced in rabbits, exhibits high specificity and reactivity with human samples, making it suitable for use in various research applications, including Western blotting.ZNRF2 is known for its role in ubiquitination and degradation of target proteins, influencing key cellular functions such as cell proliferation, differentiation, and survival. Dysregulation of ZNRF2 has been implicated in several diseases, including cancer and neurodegenerative disorders, making it a promising target for therapeutic interventions.
By using the ZNRF2 Polyclonal Antibody, researchers can effectively detect and analyze ZNRF2 expression in different cell types and tissues, providing valuable insights into its functions and potential implications in disease pathogenesis. This antibody is a valuable tool for studies in molecular biology, cell biology, and disease mechanisms, offering new opportunities for understanding and targeting ZNRF2-related pathways.
ZNRF2: May play a role in the establishment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.Protein type: Ubiquitin ligase; EC 6.3.2.19; Ubiquitin conjugating system; EC 6.3.2.-; LigaseChromosomal Location of Human Ortholog: 7p14.3Cellular Component: cytoplasm; cytoplasmic vesicle membrane; cytosol; plasma membrane; protein complexMolecular Function: ubiquitin-protein ligase activityBiological Process: protein polyubiquitination
