The ZNF75D Polyclonal Antibody (PAC021794) is a valuable tool for researchers studying the ZNF75D protein, a transcription factor involved in gene regulation and cellular processes. This antibody is produced in rabbits and exhibits high reactivity with human samples, making it suitable for use in Western blotting and immunohistochemistry applications. By binding specifically to the ZNF75D protein, researchers can accurately detect and analyze its expression in various cell types, facilitating investigations in the fields of molecular biology and cancer research.
ZNF75D is known to play a key role in controlling gene expression and influencing cellular functions, making it a target of interest in studies related to development, differentiation, and disease progression. By gaining a better understanding of ZNF75D's mechanisms of action, researchers can uncover potential therapeutic strategies for disorders such as cancer, genetic diseases, and developmental abnormalities. The ZNF75D Polyclonal Antibody offers a reliable means of investigating the functions and regulatory pathways associated with this important protein.
Antibody Name:
ZNF75D Antibody (PACO21794)
Antibody SKU:
PACO21794
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human ZNF75.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from HUVEC cells, using ZNF75 antibody.
Background:
May be involved in transcriptional regulation. Villa A., Genomics 13:1231-1236(1992).
Synonyms:
Zinc finger protein 75; Zinc finger protein 82; ZNF75; ZNF82;
UniProt Protein Function:
ZNF75D: May be involved in transcriptional regulation. Belongs to the krueppel C2H2-type zinc-finger protein family.Protein type: DNA-binding; C2H2-type zinc finger proteinChromosomal Location of Human Ortholog: Xq26.3Cellular Component: nucleusMolecular Function: sequence-specific DNA binding; transcription factor activity; zinc ion bindingBiological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein that likely functions as a transcription factor. The protein, which belongs to the ZNF75 family, includes an N-terminal SCAN domain, a KRAB box, and five C2H2-type zinc finger motifs. Another functional gene belonging to this family is located on chromosome 16, while pseudogenes have been identified on chromosomes 11 and 12. Alternative splicing results in multiple transcripts variants. [provided by RefSeq, Jun 2010]
