The ZNF598 Polyclonal Antibody (CAB15546) is a powerful tool for researchers studying ZNF598, a key protein involved in RNA quality control and protein synthesis regulation. This antibody, produced in rabbits, demonstrates high specificity and sensitivity in detecting ZNF598 in human samples, particularly in Western blot assays. By targeting the ZNF598 protein, this antibody allows for accurate identification and analysis in various cell types, making it an essential resource for investigations related to RNA metabolism, gene expression, and cellular stress responses.ZNF598, a multi-functional enzyme responsible for mRNA surveillance and ribosome quality control, plays a crucial role in maintaining cellular homeostasis by ensuring the fidelity of protein synthesis and the degradation of aberrant transcripts. Its involvement in RNA quality control pathways makes it a valuable target for research on RNA dynamics, translation regulation, and cellular stress adaptation mechanisms.
Understanding the functions of ZNF598 is essential for exploring its potential implications in genetic disorders, neurodegenerative diseases, and cancer development.In summary, the ZNF598 Polyclonal Antibody (CAB15546) offers researchers a reliable tool for investigating the functions and regulatory mechanisms of ZNF598 in cellular processes. Its high specificity, reactivity, and validation for Western blot applications make it an ideal choice for studies in molecular biology, RNA biology, and cellular signaling pathways. Unlock the potential of ZNF598 research with this cutting-edge antibody and pave the way for new discoveries in RNA quality control and
Product Name:
ZNF598 Rabbit Polyclonal Antibody
SKU:
CAB15546
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 120-420 of human ZNF598 (NP_835461.2).
Zinc-finger proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation, and apoptosis. This protein and Grb10-interacting GYF protein 2 have been identified as a components of the mammalian 4EHP (m4EHP) complex. The complex is thought to function as a translation repressor in embryonic development.
Purification Method:
Affinity purification
Gene ID:
90850
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ZNF598 Rabbit pAb (CAB15546) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15S.
