UniProt Protein Function: | ZNF473: Involved in histone 3'-end pre-mRNA processing by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex. Increases histone 3'-end pre-mRNA processing but has no effect on U7 snRNP levels, when overexpressed. Required for cell cycle progression from G1 to S phases. Belongs to the krueppel C2H2-type zinc-finger protein family.Protein type: C2H2-type zinc finger proteinChromosomal Location of Human Ortholog: 19q13.33Cellular Component: Cajal body; nucleoplasmMolecular Function: protein bindingBiological Process: histone mRNA 3'-end processing; histone mRNA metabolic process; termination of RNA polymerase II transcription |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a member of the Krueppel C2H2-type zinc-finger family of proteins. The encoded protein, a component of the U7 snRNP complex, plays a role in histone 3'-end pre-mRNA processing and may be required for cell cycle progression to S phase. Expression level and methylation status of this gene may be correlated with bone mineral density. [provided by RefSeq, Jul 2016] |
UniProt Code: | Q8WTR7 |
NCBI GenInfo Identifier: | 51702187 |
NCBI Gene ID: | 25888 |
NCBI Accession: | Q8WTR7.1 |
UniProt Secondary Accession: | Q8WTR7,Q9ULS9, Q9Y4Q7, A8K8T7 |
UniProt Related Accession: | Q8WTR7 |
Molecular Weight: | 100,182 Da |
NCBI Full Name: | Zinc finger protein 473 |
NCBI Synonym Full Names: | zinc finger protein 473 |
NCBI Official Symbol: | ZNF473Â Â |
NCBI Official Synonym Symbols: | ZN473; ZFP100Â Â |
NCBI Protein Information: | zinc finger protein 473 |
UniProt Protein Name: | Zinc finger protein 473 |
UniProt Synonym Protein Names: | Zinc finger protein 100 homolog; Zfp-100 |
Protein Family: | Zinc finger protein |
UniProt Gene Name: | ZNF473Â Â |
UniProt Entry Name: | ZN473_HUMAN |