The ZNF408 Polyclonal Antibody (CAB8512) is a crucial tool for researchers studying ZNF408, a zinc finger protein involved in various cellular processes, including gene expression regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By targeting the ZNF408 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it well-suited for investigations in molecular biology and genetic research.
ZNF408 is known to play a role in transcriptional regulation and has been implicated in the development of certain diseases, making it a promising target for therapeutic interventions. Understanding the functions and mechanisms of ZNF408 is essential for advancing our knowledge of cellular processes and disease pathology, and this antibody enables researchers to further explore the role of ZNF408 in a wide range of biological contexts.
Product Name:
ZNF408 Rabbit Polyclonal Antibody
SKU:
CAB8512
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 471-720 of human ZNF408 (NP_079017.1).
The protein encoded by this gene contains ten tandem zinc fingers and an N-terminal SET domain, so it is likely a DNA binding protein that interacts with other proteins. In adults, the encoded protein is expressed most highly in retina. Consequently, defects in this gene have been associated with familial exudative vitreoretinopathy (FEVR) and retinitis pigmentosa (RP).
Purification Method:
Affinity purification
Gene ID:
79797
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ZNF408 antibody (CAB8512) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 1s.
