ZNF397 Antibody (PACO31288)
- SKU:
- PACO31288
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
ZNF397 Antibody (PACO31288)
The ZNF397 Antibody (PAC031288) is an essential tool for researchers studying ZNF397, a transcription factor known for its role in gene regulation and cellular processes. This polyclonal antibody is produced in rabbits and is highly specific for detecting ZNF397 in human samples, making it ideal for experiments in Western blot analysis.Known to be involved in chromatin remodeling and transcriptional regulation, ZNF397 is a key player in numerous cellular functions such as cell differentiation, proliferation, and development. By targeting ZNF397 with this antibody, researchers can gain valuable insights into its function and potentially uncover new therapeutic targets for a variety of diseases.
With its high reactivity and specificity, the ZNF397 Antibody is a valuable tool for advancing research in molecular biology, genetics, and disease pathogenesis. Whether studying cancer, developmental disorders, or other conditions, this antibody provides a reliable tool for investigating the intricate workings of ZNF397 in the intricate landscape of gene regulation.
Antibody Name: | ZNF397 Antibody (PACO31288) |
Antibody SKU: | PACO31288 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Zinc finger protein 397 protein (1-275AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human testis tissue using PACO31288 at dilution of 1:100. |
Background: | Isoform 3 acts as a DNA-dependent transcriptional repressor. |
Synonyms: | Zinc finger protein 397 (Zinc finger and SCAN domain-containing protein 15) (Zinc finger protein 47), ZNF397, ZNF47 ZSCAN15 |
UniProt Protein Function: | ZNF397: Isoform 3 acts as a DNA-dependent transcriptional repressor. Belongs to the krueppel C2H2-type zinc-finger protein family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:DNA-binding; C2H2-type zinc finger protein; Transcription factor Chromosomal Location of Human Ortholog: 18q12.2 Cellular Component: cytoplasm; nucleus Molecular Function:metal ion binding; protein binding; sequence-specific DNA binding; transcription factor activity Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent |
NCBI Summary: | This gene encodes a protein with a N-terminal SCAN domain, and the longer isoform contains nine C2H2-type zinc finger repeats in the C-terminal domain. The protein localizes to centromeres during interphase and early prophase, and different isoforms can repress or activate transcription in transfection studies. Multiple transcript variants encoding different isoforms have been found for this gene. Additional variants have been described, but their biological validity has not been determined. [provided by RefSeq, Oct 2009] |
UniProt Code: | Q8NF99 |
NCBI GenInfo Identifier: | 38258943 |
NCBI Gene ID: | 84307 |
NCBI Accession: | Q8NF99.2 |
UniProt Secondary Accession: | Q8NF99,Q9BRM2, |
UniProt Related Accession: | Q8NF99 |
Molecular Weight: | 24,141 Da |
NCBI Full Name: | Zinc finger protein 397 |
NCBI Synonym Full Names: | zinc finger protein 397 |
NCBI Official Symbol: | ZNF397Â Â |
NCBI Official Synonym Symbols: | ZNF47; ZSCAN15Â Â |
NCBI Protein Information: | zinc finger protein 397 |
UniProt Protein Name: | Zinc finger protein 397 |
UniProt Synonym Protein Names: | Zinc finger and SCAN domain-containing protein 15; Zinc finger protein 47 |
Protein Family: | Zinc finger protein |
UniProt Gene Name: | ZNF397Â Â |
UniProt Entry Name: | ZN397_HUMAN |
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